{"id":3047,"date":"2023-10-30T12:05:23","date_gmt":"2023-10-30T12:05:23","guid":{"rendered":"https:\/\/wessex-sparc.com\/?page_id=3047"},"modified":"2024-03-19T14:52:05","modified_gmt":"2024-03-19T14:52:05","slug":"icm-trials","status":"publish","type":"page","link":"https:\/\/wessex-sparc.com\/icm-trials\/","title":{"rendered":"Intensive Care Medicine Trials"},"content":{"rendered":"

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This page covers active trials on Wessex intensive care units. If you wish to be involved, please contact the individual for the relevant hospital from the list below.<\/p>\r\n

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AIRWAYS-3<\/span><\/a>: A randomised trial of a supraglottic airway device vs. tracheal intubation during in-hospital cardiac arrest.<\/p>\r\n

Recruiting in: Bournemouth Hospital, Poole Hospital<\/p>\r\n

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A2B Trial<\/a><\/span>: A randomised controlled phase III trial of \u02512 agonists vs. standard care for sedation in critical care.<\/p>\r\n

Recruiting in: Poole Hospital, Southampton Hospital<\/p>\r\n

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CovEMERALD<\/a>:\u00a0A feasibility study of EMDR therapy for adult survivors of Covid-19-induced critical illness.<\/span><\/span><\/p>\r\n

Recruiting in: Poole Hospital<\/p>\r\n

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GenOMICC Study<\/a>:\u00a0<\/span>Open-source study of genetic susceptibility to death from sepsis or other critical illness.<\/p>\r\n

Recruiting in: Bournemouth Hospital, HHFT, Poole Hospital, QAH, Salisbury Hospital<\/p>\r\n

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GLASSheart Study<\/a>: <\/span>An observational study to explore the use of Global Longitudinal Strain in Septic Shock in comparison to conventional myocardial dysfunction monitoring.<\/p>\r\n

Recruiting in: QAH<\/p>\r\n

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iRehab<\/a>:<\/span> A randomised controlled trial of remote multicomponent rehabilitation vs. standard care for survivors of critical illness.<\/p>\r\n

Recruiting in: QAH<\/p>\r\n

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MARCH Trial<\/a><\/span>: A randomised controlled trial to determine whether mucoactives (carbocisteine and hypertonic saline) in critically ill patients with acute respiratory failure reduce duration of mechanical ventilation.<\/p>\r\n

Recruiting in: Bournemouth Hospital, HHFT, Poole Hospital, QAH<\/p>\r\n

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MOSAICC Trial<\/a>: <\/span>Evaluating the clinical and cost-effectiveness of bicarbonate administration for critically ill patients with AKI.<\/p>\r\n

Recruiting in: HHFT, Poole Hospital<\/p>\r\n

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REMAP-CAP Trial<\/a><\/span>: A randomised, embedded, multi-factorial, adaptive platform trial for Community-Acquired Pneumonia.<\/p>\r\n

Recruiting in: HHFT, Poole Hospital, QAH, Salisbury Hospital<\/p>\r\n

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SQUEEZE Study<\/a>: <\/span>A prospective multi-centre international observational study of postoperative vasopressor use<\/p>\r\n

Recruiting in: Bournemouth Hospital, Poole Hospital<\/p>\r\n

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SIGNET Trial<\/a>: <\/span>A trial to evaluate the benefits of simvastatin given to organ donors on outcomes in organ recipients.<\/p>\r\n

Recruiting in: Bournemouth Hospital<\/p>\r\n

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T4P Study<\/a>: <\/span>A prospective randomised trial to define the platelet count below which critically ill patients should receive a platelet transfusion prior to an invasive procedure.<\/p>\r\n

Recruiting in: HHFT, Poole Hospital<\/p>\r\n

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UK-ROX<\/a>:\u00a0<\/span>A randomised trial comparing conservative (88-92% saturations target) vs. standard care in mechanically ventilated critically ill patients.<\/p>\r\n

Recruiting in: Bournemouth Hospital, HHFT, Poole Hospital, QAH, UHS<\/p>\r\n

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VITDALIZE Study<\/a>:<\/span> The effect of high-dose vitamin D3 on 28-day mortality in adult critically ill patients with severe vitamin D deficiency.<\/p>\r\n

Recruiting at: Bournemouth Hospital<\/p>\r\n

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If you are interested in being involved in any of the above trials, please contact the research lead for the relevant hospital:<\/p>\r\n