This page covers active trials on Wessex intensive care units. If you wish to be involved, please contact the individual for the relevant hospital from the list below.

ABBRUPT Study: An RCT of Amiodarone vs Beta-blocker in new AF in ICU

Recruiting at: University Hospitals Dorset, QAH

AIRWAYS-3: A randomised trial of a supraglottic airway device vs. tracheal intubation during in-hospital cardiac arrest.

Recruiting in: University Hospitals Dorset

GenOMICC StudyOpen-source study of genetic susceptibility to death from sepsis or other critical illness.

Recruiting in: University Hospitals Dorset, HHFT, QAH, Salisbury Hospital

GUARDS Study: RCT on use of dexamethasone in ARDS 

Recruiting at: University Hospitals Dorset

MARCH Trial: A randomised controlled trial to determine whether mucoactives (carbocisteine and hypertonic saline) in critically ill patients with acute respiratory failure reduce duration of mechanical ventilation.

Recruiting in: University Hospitals Dorset, HHFT, QAH

MOSAICC Trial: Evaluating the clinical and cost-effectiveness of bicarbonate administration for critically ill patients with AKI.

Recruiting in: HHFT, University Hospitals Dorset

REMAP-CAP Trial: A randomised, embedded, multi-factorial, adaptive platform trial for Community-Acquired Pneumonia.

Recruiting in: HHFT, University Hospitals Dorset, QAH, Salisbury Hospital

SHORTER Study: Comparing antibiotic duration in treatment of sepsis in ICU

Recruiting at: Salisbury Hospital

T4P Study: A prospective randomised trial to define the platelet count below which critically ill patients should receive a platelet transfusion prior to an invasive procedure.

Recruiting in: HHFT, University Hospitals Dorset

UK-ROXA randomised trial comparing conservative (88-92% saturations target) vs. standard care in mechanically ventilated critically ill patients.

Recruiting in: University Hospitals Dorset, QAH, UHS

If you are interested in being involved in any of the above trials, please contact the research lead for the relevant hospital:

    • University Hospital Southampton – Dr. Ahilanadan Dushianthan (Dushi) – Ahilanadan.Dushianthan@uhs.nhs.uk
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    • Dorset County Hospital – Dr. Mark Pulletz – mark.pulletz@dchft.nhs.uk
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    • UHD (Bournemouth ICU) – Dr. Chee – nigel.chee@uhd.nhs.uk
    • UHD (Poole ICU) – Dr. Reschreiter – henrik.reschreiter@uhd.nhs.uk
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    • HHFT – Dr. Evetts – george.evetts@hhft.nhs.uk
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    • QAH – Dr. Pogson – david.pogson@porthosp.nhs.uk
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    • Salisbury Hospital – Dr. Couzens – christophercouzens@nhs.net